Side Effects With a Focus on Lymphadenopathy Following COVID-19 Vaccination in Pediatric and AYA Oncology Patients

J Pediatr Hematol Oncol. 2023 Mar 1;45(2):88-90. doi: 10.1097/MPH.0000000000002621. Epub 2023 Jan 19.

Abstract

The Coronavirus Disease 2019 (COVID-19) pandemic led to the swift development of multiple vaccinations. Vaccine side effects were well-documented in the healthy adult cohort and included fever and lymphadenopathy, however, side effects in the pediatric immunocompromised population have not been reported. This retrospective study investigated vaccine-eligible children and adolescent young adult oncology patients 12 to 35 years old. We found uncommon, mild, and self-limiting side effects among pediatric cancer patients and survivors. This data will help guide pediatric and AYA oncologists in providing anticipatory guidance and serve as a guide to managing lymphadenopathy as a potential confounder of malignancy.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Adolescent
  • Adult
  • COVID-19 Vaccines
  • COVID-19*
  • Child
  • Drug-Related Side Effects and Adverse Reactions*
  • Humans
  • Lymphadenopathy*
  • Neoplasms* / epidemiology
  • Retrospective Studies
  • Vaccination
  • Young Adult

Substances

  • COVID-19 Vaccines