Metformin suppresses calcium oxalate crystal-induced kidney injury by promoting Sirt1 and M2 macrophage-mediated anti-inflammatory activation

Affiliations

• ¹ Department of Urology, The First Affiliated Hospital of Anhui Medical University, 230000, Hefei, China.
• ² Bio-X, Stanford University, 94303, Stanford, California, USA.
• ³ Department of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, 430000, Wuhan, China.
• ⁴ Department of Urology, The Second Affiliated Hospital of Kunming Medical University, 650000, Kunming, China.
• ⁵ Department of Urology, The First Affiliated Hospital of Guangxi Medical University, 530000, Nanning, China.
• ⁶ Division of Urology, Department of Clinical Sciences, Intervention and Technology, Karolinska Institutet, 13820, Stockholm, Sweden.
• ⁷ Department of Urology, The First Affiliated Hospital of Xiamen University, 361000, Xiamen, China.
• ⁸ Cancer Precision Diagnosis and Treatment and Translational Medicine Hubei Engineering Research Center, 430000, Wuhan, China. xu-hua@whu.edu.cn.
• ⁹ Department of Biological Repositories, Zhongnan Hospital of Wuhan University, 430000, Wuhan, China. xu-hua@whu.edu.cn.
• ¹⁰ Department of Urology, Zhongnan Hospital of Wuhan University, 430000, Wuhan, China. xu-hua@whu.edu.cn.