First ground-based, high-field, cryogen-free, mobile intraoperative magnetic resonance imaging system

Michael L Lang; Qiang Zhang; Xiaolei Chen; Niandong Yan; Haoqin Zhu; Melanie Martin; Feng Yu; Chaoshi Niu; Gong Zhang; Qiang Zeng

doi:10.1016/j.mri.2023.01.016

First ground-based, high-field, cryogen-free, mobile intraoperative magnetic resonance imaging system

Magn Reson Imaging. 2023 Jun:99:34-40. doi: 10.1016/j.mri.2023.01.016. Epub 2023 Jan 24.

Authors

Michael L Lang¹, Qiang Zhang², Xiaolei Chen³, Niandong Yan⁴, Haoqin Zhu⁵, Melanie Martin⁶, Feng Yu⁴, Chaoshi Niu⁷, Gong Zhang⁸, Qiang Zeng⁹

Affiliations

¹ Department of Physics, University of Winnipeg, 515 Portage Ave, Winnipeg, Manitoba, Canada; Sino Canada Health Institute Inc., Winnipeg, Manitoba, Canada.
² Health Management Institute, The Second Medical Center & National Clinical Research Center for Geriatric Diseases, Chinese PLA General Hospital, 28 Fuxing Road, Beijing 100853, China; Physical Examination Center of The Affiliated Hospital of Inner Mongolia Medical University, Hohhot, Inner Mongolia 010010, China.
³ Department of Neurosurgery, Chinese PLA General Hospital, Beijing 100853, China.
⁴ Hubei Key Laboratory of Intelligent Conveying Technology and Device, Hubei Polytechnic University, Huangshi 435003, China.
⁵ Sino Canada Health Institute Inc., Winnipeg, Manitoba, Canada.
⁶ Department of Physics, University of Winnipeg, 515 Portage Ave, Winnipeg, Manitoba, Canada; Brain Engineering Centre, Anhui University, Hefei, China.
⁷ Department of Neurosurgery, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei 230001, Anhui Province, China.
⁸ Department of Physics, University of Winnipeg, 515 Portage Ave, Winnipeg, Manitoba, Canada; Anhui University of Science and Technology, Huainan 232001, China. Electronic address: m.zhang@uwinnipeg.ca.
⁹ Health Management Institute, The Second Medical Center & National Clinical Research Center for Geriatric Diseases, Chinese PLA General Hospital, 28 Fuxing Road, Beijing 100853, China.

PMID: 36702168
DOI: 10.1016/j.mri.2023.01.016

Abstract

Background/objective: Accurately targeting specific regions of interest in the brain is pivotal for the success of neurosurgical procedures. For example, the outcome of brain tumor resection is improved dramatically when surgeons are better able to define surgical borders. Intraoperative magnetic resonance imaging (iMRI) helps reduce the risk of damaging critical areas of the brain and makes it possible to confirm a successful resection or determine the need for further resection prior to closing a patient's head and finalizing the surgery. Here we present a ground-based, iMRI system with a mobile 1-T cryogen-free imager.

Methods: An ex-vivo experimental test of the novel iMRI system is performed to demonstrate preoperative and intraoperative imaging.

Results: The ground-based, mobile iMRI system presented here was successfully used to obtain intraoperative MR images without moving the imaging target or compromising conventional surgical techniques.

Conclusion: The success of this experiment constitutes a major milestone towards the installation of a ground-based, high-field, mobile iMRI system in a hospital setting.

Keywords: Cryogen-free; Ground-based iMRI; High-field mobile MRI; Neurosurgery; Porcine.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Brain / pathology
Brain Neoplasms* / pathology
Humans
Magnetic Resonance Imaging / methods
Monitoring, Intraoperative* / methods
Neurosurgical Procedures / methods