Wide-Field Fluorescein Angiography in Patients with Idiopathic Acute Anterior Uveitis

Ocul Immunol Inflamm. 2024 Apr;32(3):281-286. doi: 10.1080/09273948.2023.2168697. Epub 2023 Jan 25.

Abstract

Purpose: To elucidate whether wide-field fluorescein angiography (WFFA) can yield additional information in patients with newly diagnosed idiopathic acute anterior uveitis (AAU).

Methods: The WFFA was performed in patients with idiopathic AAU, and the findings were analyzed according to the scoring system by Angiography Scoring for Uveitis Nomenclature.

Results: Forty-four eyes of 30 patients (22 eyes of 13 patients in the pediatric group and 22 eyes of 17 patients in the adult group) were studied. The mean age was 12.41 ± 3.92 (range, 5-18) years in the pediatric group and 42.36 ± 32.07 (range, 24-68) years in the adult group. Thirteen eyes (59%) of pediatric patients and 12 eyes (54%) of adult patients showed some evidence of posterior segment activity on the WFFA (p = .764). Systemic treatment was administered in 53.8% of the pediatric and 5.9% of adult patients, depending on the disease severity.

Conclusion: Pediatric patients with idiopathic AAU may have subtle posterior segment manifestations more than adult patients, and posterior segment findings may affect the treatment preferences of physicians.

Keywords: Anterior uveitis; capillary leakage; macular leakage; optic disc hyperfluorescence; wide-field fluorescein angiography.

MeSH terms

  • Adolescent
  • Adult
  • Child
  • Eye
  • Fluorescein Angiography
  • Humans
  • Uveitis* / diagnosis
  • Uveitis, Anterior* / diagnosis