Preeclampsia and Obesity-The Preventive Role of Exercise

Int J Environ Res Public Health. 2023 Jan 10;20(2):1267. doi: 10.3390/ijerph20021267.

Abstract

Obesity is now recognized as a worldwide epidemic. An inadequate diet and reduced physical activity are acknowledged as the leading causes of excess body weight. Despite growing evidence that obesity is a risk factor for unsuccessful pregnancies, almost half of all women who become pregnant today are overweight or obese. Common complications of pregnancy in this group of women are preeclampsia and gestational hypertension. These conditions are also observed more frequently in women with excessive weight gain during pregnancy. Preeclampsia is one of the most serious pregnancy complications with an unpredictable course, which in its most severe forms, threatens the life and health of the mother and her baby. The early identification of the risk factors for preeclampsia development, including obesity, allows for the implementation of prophylaxis and a reduction in maternal and fetal complications risk. Additionally, preeclampsia and obesity are the recognized risk factors for developing cardiovascular disease in later life, so prophylaxis and treating obesity are paramount for their prevention. Thus, a proper diet and physical activity might play an essential role in the prophylaxis of preeclampsia in this group of women. Limiting weight gain during pregnancy and modifying the metabolic risk factors with regular physical exercise creates favorable metabolic conditions for pregnancy development and benefits the elements of the pathogenetic sequence for preeclampsia development. In addition, it is inexpensive, readily available and, in the absence of contraindications to its performance, safe for the mother and fetus. However, for this form of prevention to be effective, it should be applied early in pregnancy and, for overweight and obese women, proposed as an essential part of planning pregnancy. This paper aims to present the mechanisms of the development of hypertension in pregnancy in obese women and the importance of exercise in its prevention.

Keywords: exercise; gestational hypertension; obesity; preeclampsia; prophylaxis.

Publication types

  • Review
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Body Mass Index
  • Exercise
  • Female
  • Humans
  • Obesity / complications
  • Obesity / epidemiology
  • Obesity / therapy
  • Overweight / epidemiology
  • Pre-Eclampsia* / epidemiology
  • Pre-Eclampsia* / prevention & control
  • Pregnancy
  • Pregnancy Complications* / epidemiology
  • Pregnancy Complications* / prevention & control
  • Weight Gain

Grants and funding

This research was funded by the Medical University of Lublin, grant number 333.