Use of analgesics in Denmark: A national survey

Basic Clin Pharmacol Toxicol. 2023 Apr;132(4):321-327. doi: 10.1111/bcpt.13837. Epub 2023 Jan 27.

Abstract

People suffering from pain constitute a sizeable and heterogeneous patient group. Conventional oral analgesics are considered a cheap and safe first-line treatment. These drugs are used on both a regular and 'as needed' basis and are often obtained over-the-counter (OTC). We explored patient-reported patterns of use and adverse effects of analgesics in a community pharmacy questionnaire. Eight pharmacies invited persons aged ≥18 years requesting analgesics via prescription or OTC to complete an electronic questionnaire. A total of 2410 participants completed the questionnaire (68% female; 50% ≥ 60 years). Most participants filled a prescription for paracetamol (61%; n = 842) and non-steroidal analgesics (n = 363; 26%). Among OTC users, most obtained paracetamol (61%). Among prescription users, 73% (n = 1114) had their analgesic prescribed for daily use; however, of these only 61% (n = 630) reported using it daily, while 35% (n = 363) reported 'as needed' use. Of all prescriptions, 80% (n = 898) were labelled with the standardized indication 'against pain'. Self-reported indications showed that back pain and muscle/joint pain were the most common indications. Among non-new users of OTC analgesics (n = 841), 17% (n = 141) used their medication daily. Finally, 90% (n = 1658) of all participants reported not experiencing adverse effects. Our findings suggest a need for continuous assessment of analgesic patterns of use after treatment initiation to inform counselling in community pharmacies and elsewhere.

Keywords: adverse effects; analgesics; community pharmacy; patterns of drug use; questionnaire.

MeSH terms

  • Acetaminophen* / therapeutic use
  • Adolescent
  • Adult
  • Analgesics / therapeutic use
  • Denmark
  • Drug-Related Side Effects and Adverse Reactions*
  • Female
  • Humans
  • Male
  • Nonprescription Drugs / adverse effects
  • Pain / drug therapy

Substances

  • Acetaminophen
  • Analgesics
  • Nonprescription Drugs