A rare case of cytomegalovirus hepatitis mimicking malignancy in an immunocompetent adult

Nimisha Manek; Samuel Conyngham; Melinda Tram Thi Ngoc Nguyen; Thao Lam; Chow P'Ng; Anthony Peduto

doi:10.1016/j.radcr.2022.12.030

A rare case of cytomegalovirus hepatitis mimicking malignancy in an immunocompetent adult

Radiol Case Rep. 2023 Jan 11;18(3):1164-1168. doi: 10.1016/j.radcr.2022.12.030. eCollection 2023 Mar.

Authors

Nimisha Manek¹, Samuel Conyngham¹, Melinda Tram Thi Ngoc Nguyen², Thao Lam², Chow P'Ng³, Anthony Peduto¹

Affiliations

¹ Department of Radiology, Westmead Hospital, Cnr Hawkesbury Road and, Darcy Rd, Westmead, NSW 2145, Australia.
² Department of Gastroenterology, Westmead Hospital, Westmead, NSW, 2145, Australia.
³ Department of Pathology, Westmead Hospital, Westmead, NSW, 2145, Australia.

Abstract

Cytomegalovirus (CMV) is a highly prevalent pathogen that remains dormant in majority of the cases. Severe CMV infection is generally limited to immunocompromised hosts. While occasional cases of CMV hepatitis are observed in healthy immunocompetent hosts, it is very rare to find this associated with focal liver lesions mimicking malignancy. Cases of non-immunosuppressed CMV reactivation, CMV-associated liver lesions, and CMV-associated portal vein thrombosis have all been reported individually, we present a single case of CMV with all of these rare manifestations.

Keywords: Cytomegalovirus; Hepatitis; Immunocompetent; Liver lesion(s), Malignancy.

Publication types

Case Reports