Systems biology of protein network

Biophys Rev. 2022 Dec 13;14(6):1231-1232. doi: 10.1007/s12551-022-01023-8. eCollection 2022 Dec.

Abstract

The development of comprehensive measurement technology for biomolecules and the development of computer hardware and algorithms, enhanced by human genome research, have greatly contributed to the advancement of predictive biology. However, to make that happen, it was essential to have a common concept of sharing data in a standard format. In this article, I would like to briefly review how such concepts were developed in Japan for the foundation of today's biological sciences.

Keywords: Computational simulation; Mathematical modeling; Protein folding; Signaling network; Trajectories.