Solitary cardiac metastasis of urothelial carcinoma of the urinary bladder with squamous cell differentiation - a rare manifestation

Gregor Duwe; Nikita Dhruva Fischer; Maximilian Haack; Thomas Höfner; Axel Haferkamp; Maximilian Peter Brandt

doi:10.1016/j.eucr.2023.102318

Solitary cardiac metastasis of urothelial carcinoma of the urinary bladder with squamous cell differentiation - a rare manifestation

Urol Case Rep. 2023 Jan 2:46:102318. doi: 10.1016/j.eucr.2023.102318. eCollection 2023 Jan.

Authors

Gregor Duwe¹, Nikita Dhruva Fischer¹, Maximilian Haack¹, Thomas Höfner¹, Axel Haferkamp¹, Maximilian Peter Brandt¹

Affiliation

¹ Department of Urology and Pediatric Urology, Johannes-Gutenberg University Medical Center, Mainz, Germany.

Abstract

We present a case of bladder cancer with a singular cardiac metastasis. A 51-year-old female patient was referred to our department for painless macrohematuria. We confirmed the diagnosis of muscle-invasive urothelial carcinoma of the urinary bladder with partial squamous cell differentiation. Computed tomography (CT) staging demonstrated a singular cardiac metastasis. Two months after receiving six cycles of chemotherapy control CT scan revealed massive tumour progression. The singular cardiac metastasis size increased to approximately two thirds of right ventricle size. Singular cardiac metastases of urothelial carcinoma are extremely rare and show rapid progression, hence introduction to therapy should not be delayed.

Keywords: Cardiac metastasis; Squamous cell differentiation; Urothelial cancer.

Publication types

Case Reports