How each individual within a relationship views their body may play a role in how they experience their sexual interactions. Previous research found associations between body image and sexual well-being at an individual level, but very little research has examined a dyadic association between body image and sexual and relational well-being. Using a nationally representative sample of 2,177 newlywed couples, this study used an Actor-Partner Interdependence Mediation Model (APIMeM) to estimate actor and partner associations between body esteem and relationship satisfaction, using sexual styles - inhibited, obsessed, or harmonious - as potential mediators. Findings showed both actor and partner effects. Body esteem was positively associated with own and partner's sexual harmony. Both men's and women's body esteem were negatively associated with women's sexual inhibition. A positive association between body esteem and own relationship satisfaction remained even when accounting for sexual mediators. Additional findings are discussed. These findings indicate that an individual's comfort with the body may be associated with sexual and relational well-being for both partners.