Pulmonary Hypertension Definition, Classification, and Epidemiology in Asia

James J Anderson; Edmund M Lau

doi:10.1016/j.jacasi.2022.04.008

Pulmonary Hypertension Definition, Classification, and Epidemiology in Asia

JACC Asia. 2022 Aug 2;2(5):538-546. doi: 10.1016/j.jacasi.2022.04.008. eCollection 2022 Oct.

Authors

James J Anderson^{1

2}, Edmund M Lau^{3

4}

Affiliations

¹ Respiratory Department, Sunshine Coast University Hospital, Birtinya, Queensland, Australia.
² School of Medicine, Griffith University, Southport, Queensland, Australia.
³ Respiratory Department, Royal Prince Alfred Hospital, Camperdown, New South Wales, Australia.
⁴ Faculty of Medicine and Health, University of Sydney, Camperdown, New South Wales, Australia.

Abstract

Pulmonary hypertension (PH) is caused by a range of conditions and is important to recognize as it is associated with increased mortality. Pulmonary arterial hypertension refers to a group of PH subtypes affecting the distal pulmonary arteries for which effective treatment is available. The hemodynamic definition of pulmonary arterial hypertension has recently changed which may lead to greater case recognition and earlier treatment. The prevalence of specific PH etiologies may differ depending on geographic region. PH caused by left heart disease is the most common cause of PH worldwide. In Asia, there is greater proportion of congenital heart disease- and connective tissue disease- (especially systemic lupus erythematosus) related PH relative to the West. This review summarizes the definition, classification, and epidemiology of PH as it pertains to Asia.

Keywords: Asia; BPA, balloon pulmonary angioplasty; PAH, pulmonary arterial hypertension; PH, pulmonary hypertension; RHC, right heart catheterization; WSPH, World Symposium on Pulmonary Hypertension; pulmonary arterial hypertension.

Publication types

Review