Dosimetric characterization of a novel commercial plastic scintillation detector with an MR-Linac

Med Phys. 2023 Apr;50(4):2525-2539. doi: 10.1002/mp.16204. Epub 2023 Jan 16.

Abstract

Background: Plastic scintillators have been used as radiation detectors for the past few years, as they are water-equivalent and independent of the dose, dose rate, and angle of incidence. In addition, they are also independent of the presence of a magnetic field and could be used for in vivo dosimetry in an MR-Linac. With the advent of a new commercial scintillation detector, Blue Physics Model 10, its characterization has been performed on an MR-Linac with a view to future applications.

Purpose: To perform the dosimetric characterization and study potential applications of a novel commercial plastic scintillation detector in a MR-Linac.

Methods: Scintillation detector description, calibration procedure, short-term repeatability, dose-response linearity, dose-rate dependence, angular dependence, and temperature dependence have been studied. Percent-depth-dose (PDD) and beam profiles were measured for small fields and a standard field, as well as output factors, for comparison with other PTW detectors: a diamond diode and PinPoint and Semiflex 3D ionization chambers. The suitability of the plastic scintillator for in vivo dosimetry in a magnetic field has also been studied measuring the dose to a point in an anthropomorphic phantom while acquiring MR imaging. This measured dose was compared with that calculated with Monaco planning system and with that measured with a PTW Semiflex 3D chamber, the latter without acquiring MR images.

Results: Short-term repeatability presented negligible variations (<0.4%) for 100 and 20 MU. Similar results were obtained for dose-response linearity and dose-rate dependence. A small angular dependence was determined, while the scintillator resulted practically independent of the temperature. PDDs showed excellent agreement except in the build-up region, and calculated penumbras with the profiles given by the scintillator were between the ones obtained with the diamond detector and the PinPoint ionization chamber. Measured OF with the scintillator were the highest between all detectors, 1.26% higher than the value obtained with the microdiamond for the smallest field measured, 0.5 × 0.5 cm2 . Finally, the total dose to a point measured with the scintillator was 0.51% higher compared to that calculated by the planning system.

Conclusion: The Blue Physics model 10 scintillation system showed excellent dosimetric characteristics. Its response independent of the temperature and the presence of a magnetic field make it suitable for in vivo dosimetry in an MR-Linac while acquiring MR images, which could solve the impossibility of performing a dosimetric QA for each adapted plan. Furthermore, its temporal resolution allows independent radiation pulses to be measured and visualized, which could be used in future applications.

Keywords: MR-Linac; dosimeter characterization; in vivo dosimetry; scintillator dosimeter.

MeSH terms

  • Diamond
  • Magnetic Resonance Imaging
  • Photons
  • Plastics*
  • Radiometry* / methods
  • Water

Substances

  • Plastics
  • Water
  • Diamond