Management of Gastric Cancer

Am Surg. 2023 Jun;89(6):2713-2720. doi: 10.1177/00031348221148359. Epub 2023 Jan 7.

Abstract

Gastric adenocarcinoma is a complex disease that requires a thorough multidisciplinary approach for appropriate management. Management strategies vary in different regions of the world and have changed over time. In spite of improvements in chemotherapy and surgical techniques and an improvement in outcomes over the last several decades, overall survival remains low. The best outcomes are likely related to early detection, preoperative reduction of tumor burden with immunochemotherapy, consistent surgical technique for resection, and postoperative eradication of tumor cells. We aim to describe the management for gastric cancer, from the specifics of staging and imaging workup to the tenets of surgical resection and reconstruction as well as the adjuvant treatment strategies in this broad review of gastric cancer management.

Keywords: esophagus/foregut; gastrointestinal; history; surgical oncology.

Publication types

  • Review

MeSH terms

  • Adenocarcinoma* / diagnosis
  • Adenocarcinoma* / surgery
  • Chemotherapy, Adjuvant
  • Gastrectomy
  • Humans
  • Stomach Neoplasms* / diagnosis
  • Stomach Neoplasms* / surgery