Relationship of Kidney Tubule Biomarkers with Cognition among Community-Living Elders in the Health ABC Study

Kidney360. 2022 Oct 20;3(12):2106-2109. doi: 10.34067/KID.0004022022. eCollection 2022 Dec 29.

Abstract

Higher baseline urinary neutrophil gelatinase-associated lipocalin was associated with worse cognitive scores at baseline.Lower concentrations of baseline serum bicarbonate (higher is better) were associated with lower cognitive scores at baseline.We found no associations with urine markers with longitudinal changes in cognition.

Keywords: biomarkers; chronic kidney disease; cognition; kidney tubules.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, U.S. Gov't, Non-P.H.S.
  • Research Support, N.I.H., Intramural

MeSH terms

  • Biomarkers
  • Cognition*
  • Kidney Tubules*

Substances

  • Biomarkers