Smartphone-based single snapshot spatial frequency domain imaging

Jesse H Lam; Kelsey J Tu; Jeonghun Kim; Sehwan Kim

doi:10.1364/BOE.470665

Smartphone-based single snapshot spatial frequency domain imaging

Biomed Opt Express. 2022 Nov 16;13(12):6497-6507. doi: 10.1364/BOE.470665. eCollection 2022 Dec 1.

Authors

Jesse H Lam¹, Kelsey J Tu², Jeonghun Kim^{2

3}, Sehwan Kim^{2

4}

Affiliations

¹ Dankook University, Beckman Laser Institute Korea, School of Medicine, Cheonan, Chungnam, Republic of Korea.
² Dankook University, Department of Biomedical Engineering, Cheonan, Chungnam, Republic of Korea.
³ MEDiThings Co. Ltd., Industry-Academia Cooperation, Dankook University, Cheonan, Chungnam, Republic of Korea.
⁴ University of California, Irvine, Beckman Laser Institute, Department of Biomedical Engineering, Irvine, CA, USA.

Abstract

We report a handheld, smartphone-based spatial frequency domain imaging device. We first examined the linear dynamic range of the smartphone camera sensor. We then calculated optical properties for a series of liquid phantoms with varying concentrations of nigrosin ink and Intralipid, demonstrating separation of absorption and scattering. The device was then tested on a human wrist, where optical properties and hemoglobin-based chromophores were calculated. Finally, we performed an arterial occlusion on a human hand and captured hemodynamics using our device. We hope to lay the foundation for an accessible SFDI device with mass-market appeal designed for dermatological and cosmetic applications.