5-aminolevulinic acid photodynamic therapy combined with wart curettage treatment for intractable urethral condylomata acuminata. A case report

Photodiagnosis Photodyn Ther. 2023 Mar:41:103264. doi: 10.1016/j.pdpdt.2022.103264. Epub 2022 Dec 29.

Abstract

Condylomata acuminata (CA) is caused by human papillomavirus (HPV). It is one of the most common sexually transmitted diseases (STD). The lesions mainly occur in the external genitalia and perianal areas, rarely involves in urethral and usually localized at the distal 3 cm of the urethral orifice. Because of the special anatomical site, treating urethral CA is challenging and it has high recurrence rate after treatment. 5-aminolevulinic acid photodynamic therapy (ALA-PDT) can successfully treat urethral CA, however, the experience of using ALA-PDT combined with wart curettage to treat intractable urethral CA is still very limited. In here, we reported an intractable urethral CA case with effective remission after receiving combination therapy. Wart curettage combine with ALA-PDT is an expeditious, economical, and well-tolerated treatment method.

Keywords: 5-aminolevulinic acid photodynamic therapy; Condylomata acuminata; Human papillomavirus; Wart curettage.

Publication types

  • Case Reports

MeSH terms

  • Aminolevulinic Acid / therapeutic use
  • Condylomata Acuminata* / drug therapy
  • Condylomata Acuminata* / surgery
  • Curettage
  • Humans
  • Papillomaviridae
  • Photochemotherapy* / methods
  • Photosensitizing Agents / therapeutic use

Substances

  • Aminolevulinic Acid
  • Photosensitizing Agents