How respiratory symptoms impact asthma-related quality of life in mild asthmatics

Gilles Louis; Florence Schleich; Renaud Louis; Michèle Guillaume; Bernardo Sousa-Pinto; Jean Bousquet; Benoit Pétré

doi:10.1016/j.rmed.2022.107098

How respiratory symptoms impact asthma-related quality of life in mild asthmatics

Respir Med. 2023 Feb:207:107098. doi: 10.1016/j.rmed.2022.107098. Epub 2022 Dec 28.

Authors

Gilles Louis¹, Florence Schleich², Renaud Louis², Michèle Guillaume³, Bernardo Sousa-Pinto⁴, Jean Bousquet⁵, Benoit Pétré³

Affiliations

¹ Department of Public Health, University of Liège, Belgium. Electronic address: glouis@uliege.be.
² Department of Pneumology, GIGAI3, University of Liège, Belgium.
³ Department of Public Health, University of Liège, Belgium.
⁴ Department of Community Medicine, Information and Health Decision Sciences, Faculty of Medicine, University of Porto, Porto, Portugal.
⁵ Institute of Allergology, Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany; Fraunhofer Institute for Translational Medicine and Pharmacology ITMP, Allergology and Immunology, Berlin, Germany; University Hospital Montpellier, France.

PMID: 36584792
DOI: 10.1016/j.rmed.2022.107098

Abstract

Many studies exploring the factors associated with asthma-specific quality of life (QOL) have shown that asthma control is the main predictor of asthma-related QOL. However, to the best of our knowledge, no study has ever explored the individual impact of the five main symptoms of asthma (wheezing, dyspnea, chest tightness, cough and airway secretion) reported directly by the patient on asthma-related QOL. A cross-sectional study was conducted on untreated adult (≥18 years) asthmatics recruited from the Liege University Hospital Asthma Clinic (Belgium) for asthma diagnosis confirmation between 2018 and 2021 (n = 171). Multiple linear regression analysis demonstrated that dyspnea and chest tightness were the two leading factors associated with asthma-related QOL in a population of mild asthma.

Keywords: Asthma; PROM; Quality of life; Symptoms.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Adult
Asthma* / complications
Asthma* / epidemiology
Cross-Sectional Studies
Dyspnea / complications
Humans
Quality of Life*
Respiratory System
Surveys and Questionnaires