Background : Pharmacist-led transitions of care between hospital and community settings have been associated with decreased hospitalizations. Little data is available on the optimal conditions for their implantation.Purpose of research : The study aims to analyze the implementation of a pharmacist-led transition of care intervention among older adults with drug-related problems. The objectives are to describe the main characteristics of the intervention and to identify the facilitators and the barriers to its implementation.Methods : A single case study design including individual interviews (n = 10 interviews) and document analysis was preferred. Damschroder’s conceptual implementation framework guided the analysis.Results : The main characteristics of the intervention are the interdisciplinary collaboration and clarity of the involved professional’s roles, the time dedicated to the intervention and the improvement of interdisciplinary communication mechanisms. The implementation facilitators include the availability of leaders and clinical champion, as well as the perception and collaboration of professionals. The Barriers include the limitations in integrating the intervention into routine care in terms of time and resources, the adoption and lack of skills in using an electronic medical record and the difficult access to some patients for follow-ups.Conclusions : The analysis of the main characteristics of the intervention, the facilitators and the barriers to its implementation demonstrate the feasibility of this pharmacist-led transition of care intervention and the issues associated with its integration into routine care in the Canadian health system.