We report a case-series study of 5 patients with Japanese spotted fever from the Three Gorges Area in China, including 1 fatal case. Seroprevalence of Rickettsia japonica was ≈21% among the local population. Our report highlights the emerging potential threat to human health of Japanese spotted fever in the area.
Keywords: China; Japanese spotted fever; Rickettsia japonica; bacteria; cytokines; fatal outcomes; febrile illnesses; rickettsia; tickborne illnesses; vector-borne infections.