In late 2021, highly pathogenic avian influenza A(H5N8) clade 2.3.4.4b viruses were detected in domestic ducks in poultry markets in Cambodia. Surveillance, biosafety, and biosecurity efforts should be bolstered along the poultry value chain to limit spread and infection risk at the animal-human interface.
Keywords: Cambodia; H5N8; avian influenza virus; disease surveillance; food safety; influenza; live poultry markets; pathogenic; phylogenetics; respiratory infections; viruses; whole-genome sequencing; zoonoses.