Monkeypox: potential vaccine development strategies

Trends Pharmacol Sci. 2023 Jan;44(1):15-19. doi: 10.1016/j.tips.2022.10.005. Epub 2022 Dec 8.

Abstract

A multicountry outbreak of monkeypox has gained global attention. Basic research including structural and immunological investigation on monkeypox virus (MPXV) is central to design effective solutions of treatment with antivirals and appropriate vaccines. We summarize some information about this virus and its re-emergence and the current vaccines that are proposed to limit its spread and present some possible avenues for developing new vaccines.

Keywords: emerging infection; orthopoxvirus; peptides; smallpox; synthetic vaccines.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Humans
  • Monkeypox virus
  • Mpox (monkeypox)* / prevention & control