The Metastatic Process through the Eyes of Epigenetic Regulation: A Promising Horizon for Cancer Therapy

Bozena Smolkova; Julie Earl; Agapi Kataki

doi:10.3390/ijms232415446

The Metastatic Process through the Eyes of Epigenetic Regulation: A Promising Horizon for Cancer Therapy

Int J Mol Sci. 2022 Dec 7;23(24):15446. doi: 10.3390/ijms232415446.

Authors

Bozena Smolkova¹, Julie Earl², Agapi Kataki³

Affiliations

¹ Department of Molecular Oncology, Cancer Research Institute, Biomedical Research Center of the Slovak Academy of Sciences, Dubravska Cesta 9, 845-05 Bratislava, Slovakia.
² Molecular Epidemiology and Predictive Tumor Markers Group, Medical Oncology Research Laboratory, Ramón y Cajal Health Research Institute (IRYCIS), Carretera Colmenar Km 9100, CIBERONC, 28034 Madrid, Spain.
³ 1st Department of Propaedeutic Surgery, National and Kapodistrian University of Athens, Vasilissis Sofias 114, 11527 Athens, Greece.

Abstract

Genetic aberrations, including chromosomal rearrangements, loss or amplification of DNA, and point mutations, are major elements of cancer development [...].

Publication types

Editorial

MeSH terms

Chromosome Aberrations
DNA
Epigenesis, Genetic*
Humans
Neoplasms* / genetics
Neoplasms* / therapy
Point Mutation

Substances

DNA

Abstract

Publication types

MeSH terms

Substances

Grants and funding