Systemic Lymphadenopathic Mastocytosis with Eosinophilia

Soyoung Im; Jeong-A Kim; Gyeongsin Park; Uiju Cho

doi:10.3390/diagnostics12123057

Systemic Lymphadenopathic Mastocytosis with Eosinophilia

Diagnostics (Basel). 2022 Dec 6;12(12):3057. doi: 10.3390/diagnostics12123057.

Authors

Soyoung Im¹, Jeong-A Kim², Gyeongsin Park³, Uiju Cho¹

Affiliations

¹ Department of Pathology, St. Vincent's Hospital, College of Medicine, The Catholic University of Korea, Seoul 06591, Republic of Korea.
² Department of Internal Medicine, St. Vincent's Hospital, College of Medicine, The Catholic University of Korea, Seoul 06591, Republic of Korea.
³ Department of Pathology, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul 06591, Republic of Korea.

Abstract

Systemic mastocytosis is a neoplastic proliferation of mast cells that most frequently involves cutaneous sites. Mastocytosis involves various extracutaneous sites, but the lymph node is rare. We present an interesting image of systemic mastocytosis in the lymph node with marked eosinophilia. It is a rare subtype of systemic mastocytosis requiring high suspicion levels for the correct diagnosis.

Keywords: eosinophilia; lymphadenopathy; mastocytosis; systemic mastocytosis.

Grants and funding

This research was supported by Basic Science Research Program through the National Research Foundation of Korea (NRF) funded by the Ministry of Education (NRF- 2022R1I1A1A01071569).