Inhibition of White Spot Syndrome Virus (WSSV) in Pacific White Shrimp (Litopenaeus vannamei) Using Polyamine-Modified Carbon Quantum Dots

Hung-Yun Lin; John Han-You Lin; Han-Jia Lin; Li-Li Chen

doi:10.1007/978-1-0716-2895-9_6

Inhibition of White Spot Syndrome Virus (WSSV) in Pacific White Shrimp (Litopenaeus vannamei) Using Polyamine-Modified Carbon Quantum Dots

Methods Mol Biol. 2023:2610:67-73. doi: 10.1007/978-1-0716-2895-9_6.

Authors

Hung-Yun Lin¹, John Han-You Lin², Han-Jia Lin³, Li-Li Chen^{4

5}

Affiliations

¹ Center of Excellence for the Oceans, National Taiwan Ocean University, Keelung, Taiwan, Republic of China.
² School of Veterinary Medicine, National Taiwan University, Taipei, Taiwan, Republic of China.
³ Department of Bioscience and Biotechnology, National Taiwan Ocean University, Keelung, Taiwan, Republic of China.
⁴ Institute of Marine Biology, National Taiwan Ocean University, Keelung, Taiwan, Republic of China. joechen@ntou.edu.tw.
⁵ Center of Excellence for the Oceans, National Taiwan Ocean University, Keelung, Taiwan, Republic of China. joechen@ntou.edu.tw.

PMID: 36534282
DOI: 10.1007/978-1-0716-2895-9_6

Abstract

White spot syndrome virus (WSSV), an enveloped double-stranded DNA virus, is the causative agent of white spot syndrome (WSS), which has been linked to cultured shrimp mass mortality in many countries. Therefore, the development of anti-WSSV agents is among the top priorities of the aquaculture sector. Here, we describe the preparation of polyamine-modified carbon quantum dots (polyamine CQDs) for the treatment of WSSV. Moreover, in vivo experiments were conducted in shrimp to confirm the anti-WSSV effect of the proposed CQD-based strategy.

Keywords: Anti-WSSV strategies; Aquaculture; In vivo experiment; Polyamine-modified carbon quantum dots; Shrimps; White spot syndrome virus.

MeSH terms

Animals
Carbon
Penaeidae*
Polyamines / pharmacology
Quantum Dots*
White spot syndrome virus 1* / genetics

Substances

Carbon
Polyamines