Crystal structure of vaccinia virus G3/L5 sub-complex reveals a novel fold with extended inter-molecule interactions conserved among orthopoxviruses

Sheng Lin; Dan Yue; Fanli Yang; Zimin Chen; Bin He; Yu Cao; Haohao Dong; Jian Li; Qi Zhao; Guangwen Lu

doi:10.1080/22221751.2022.2160661

Crystal structure of vaccinia virus G3/L5 sub-complex reveals a novel fold with extended inter-molecule interactions conserved among orthopoxviruses

Emerg Microbes Infect. 2023 Dec;12(1):e2160661. doi: 10.1080/22221751.2022.2160661.

Authors

Sheng Lin¹, Dan Yue¹, Fanli Yang¹, Zimin Chen¹, Bin He¹, Yu Cao^{1

2}, Haohao Dong³, Jian Li⁴, Qi Zhao⁵, Guangwen Lu¹

Affiliations

¹ West China Hospital Emergency Department (WCHED), State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu, People's Republic of China.
² Disaster Medicine Center, West China Hospital, Sichuan University, Chengdu, People's Republic of China.
³ Laboratory of Aging Research and Cancer Drug Target, State Key Laboratory of Biotherapy and Cancer Center, National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University, Chengdu, People's Republic of China.
⁴ School of Basic Medical Sciences, Chengdu University, Chengdu, People's Republic of China.
⁵ College of Food and Biological Engineering, Chengdu University, Chengdu, People's Republic of China.

No abstract available

Publication types

Letter

MeSH terms

HeLa Cells
Humans
Orthopoxvirus* / genetics
Vaccinia virus* / genetics

Grants and funding

This work was supported by the National Natural Science Foundation of China [grant number 81971925] and the 1.3.5 project for disciplines of excellence, West China Hospital, Sichuan University [grant number ZYYC20008].