Comparison between MCNP and planning system in brachytherapy of cervical cancer

Dragana Krstic; Dragoslav Nikezic; Marija Z Jeremic; Edin Dolicanin; Tatjana B Miladinovic; Milena Zivkovic

doi:10.1016/j.apradiso.2022.110614

Comparison between MCNP and planning system in brachytherapy of cervical cancer

Appl Radiat Isot. 2023 Feb:192:110614. doi: 10.1016/j.apradiso.2022.110614. Epub 2022 Dec 10.

Authors

Dragana Krstic¹, Dragoslav Nikezic², Marija Z Jeremic³, Edin Dolicanin⁴, Tatjana B Miladinovic⁵, Milena Zivkovic⁶

Affiliations

¹ University of Kragujevac, Faculty of Science, Serbia. Electronic address: dragana@kg.ac.rs.
² University of Kragujevac, Faculty of Science, Serbia; State University of Novi Pazar, Serbia. Electronic address: nikezic@kg.ac.rs.
³ University Clinical Center Kragujevac, Serbia. Electronic address: marijafiz@yahoo.com.
⁴ State University of Novi Pazar, Serbia. Electronic address: edin@np.ac.rs.
⁵ University of Kragujevac, Institute for Information Technologies, Serbia. Electronic address: tanja.miladinovic@gmail.com.
⁶ University of Kragujevac, Faculty of Science, Serbia. Electronic address: milena.zivkovic@pmf.kg.ac.rs.

PMID: 36527853
DOI: 10.1016/j.apradiso.2022.110614

Abstract

Absorbed doses in uterus during brachytherapy were calculated with MCNP in relevant points and compared with planning system for one patients. MCNP was applied with two different humanoid phantoms in input, ORNL and voxel models, which represent human body in mathematical way. Good agreement between both phantoms, as well as, between MCNP and planning system were found. In addition the doses in critical organs (bladder and colon in this kind of therapy), were calculated and compared with maximal doses in these organs obtained from planning system for 15 other patients. MCNP doses agree well with planning system in points of uterus for those 15 patients, where radioactive source is used to apply. However, there are systematical discrepancies between doses in colon and bladder obtained by MCNP and planning system.

Keywords: Absorbed dose; Brachytherapy; Conversion coefficients; MCNP; Monte Carlo.

MeSH terms

Brachytherapy* / methods
Female
Humans
Monte Carlo Method
Phantoms, Imaging
Radiotherapy Dosage
Radiotherapy Planning, Computer-Assisted / methods
Uterine Cervical Neoplasms* / diagnostic imaging
Uterine Cervical Neoplasms* / radiotherapy