Natural polyphenols: a promising bioactive compounds for skin care and cosmetics

Mol Biol Rep. 2023 Feb;50(2):1817-1828. doi: 10.1007/s11033-022-08156-9. Epub 2022 Dec 9.

Abstract

The physiological and morphological aspects of skin suffer from frequent change. Numerous internal and external factors have direct impact on inducing various skin problems like inflammation, aging, cancer, oxidative stress, hyperpigmentation etc. The use of plant polyphenols as a photo-ecting agent is gaining popularity nowadays. Polyphenols are known to enhance endogenic antioxidant system of skin thereby preventing various skin diseases. The biological activity of plant polyphenols is dependent on their physicochemical properties for overcoming the epidermal barriers to reach the specific receptor. Several evidences have reported the vital role polyphenols in mitigating adverse skin problems and reverting back the healthy skin condition. The interest in plant derived skin care products is emerging due to the changing notion of people to shift their focus towards use of plant-based products. The present review draws an attention to uncover the protective role of polyphenols in prevention of various skin problems. Several in vitro and in vivo studies have been summarized that claims the efficacious nature of plant extract having dermatological significance.

Keywords: Anti-aging; Anti-melanogenesis; Antioxidant; Photoprotectant; Polyphenols; Skin.

Publication types

  • Review

MeSH terms

  • Antioxidants / pharmacology
  • Cosmetics*
  • Humans
  • Plant Extracts / chemistry
  • Plant Extracts / pharmacology
  • Plant Extracts / therapeutic use
  • Plants
  • Polyphenols* / chemistry
  • Polyphenols* / pharmacology
  • Polyphenols* / therapeutic use
  • Skin
  • Skin Care

Substances

  • Polyphenols
  • Antioxidants
  • Cosmetics
  • Plant Extracts