TRPV4 and the paradox of faster cellular migration rates in more viscous extracellular fluids

Cell Calcium. 2023 Jan:109:102685. doi: 10.1016/j.ceca.2022.102685. Epub 2022 Dec 5.

Authors

Choon Leng So¹, Mélanie Robitaille², Gregory R Monteith³

Affiliations

¹ Department of Biochemistry and Molecular Biology, Johns Hopkins School of Public Health, Baltimore, MD, United States of America.
² School of Pharmacy, The University of Queensland, Brisbane, Queensland, Australia.
³ School of Pharmacy, The University of Queensland, Brisbane, Queensland, Australia. Electronic address: gregm@uq.edu.au.

PMID: 36493538
DOI: 10.1016/j.ceca.2022.102685

No abstract available

Keywords: Cancer, Cell migration; Epithelial-mesenchymal transition; TRPM7; TRPV4.

Publication types

Review
Research Support, Non-U.S. Gov't

MeSH terms

Cell Line, Tumor
Cell Movement* / physiology
Extracellular Fluid* / metabolism
Protein Serine-Threonine Kinases / metabolism
TRPV Cation Channels*

Substances

Protein Serine-Threonine Kinases
TRPV Cation Channels