Teaching old drugs new tricks

Elife. 2022 Dec 8:11:e84702. doi: 10.7554/eLife.84702.

Abstract

Understanding the mechanism by which streptomycin binds to the small subunit of the mitoribosome may help researchers design less toxic derivatives of this antibiotic.

Keywords: Fe-S cluster; antibiotics; bacteria; human; mitochondria; mitoribosome; molecular biophysics; ototoxicity; structural biology.

Publication types

  • Editorial