Examining the cooperation between extrachromosomal DNA circles

Elife. 2022 Dec 7:11:e84639. doi: 10.7554/eLife.84639.

Abstract

In a departure from previous findings, new results suggest that free-floating pieces of DNA which carry additional copies of cancer-driving genes do not tend to cluster or have increased transcription.

Keywords: cancer; chromosomes; extrachromosomal DNA; gene expression; glioblastoma; human; oncogenes; super-resolution imaging; transcription factors hub.

Publication types

  • Editorial
  • Comment

MeSH terms

  • DNA* / genetics

Substances

  • DNA