Lumbar Spinal Canal Stenosis in Acromegaly: A Case Report and Literature Review

Intern Med. 2023 Jul 15;62(14):2093-2098. doi: 10.2169/internalmedicine.0763-22. Epub 2022 Dec 7.

Abstract

A 60-year-old Japanese man diagnosed with acromegaly at 28 years old had difficulty walking due to worsening back pain. He had been treated with somatostatin analog since 57 years old, but his pain and numbness continued to worsen. Lumbar magnetic resonance imaging showed disc bulging at L3/4 and L4/5, and he was diagnosed with lumbar spinal canal stenosis due to hypertrophy of the yellow ligament. Patients with acromegaly may complain of osteoarthropathy, so we must pay attention to the symptoms of spinal canal stenosis in collaboration with orthopedic specialists.

Keywords: IGF-1; acromegaly; hypertrophy of yellow ligament; insulin-like growth factor-1; osteoarthropathy; spinal canal stenosis.

Publication types

  • Review
  • Case Reports

MeSH terms

  • Acromegaly* / complications
  • Acromegaly* / diagnosis
  • Adult
  • Back Pain
  • Constriction, Pathologic
  • Humans
  • Lumbar Vertebrae / diagnostic imaging
  • Magnetic Resonance Imaging
  • Male
  • Middle Aged
  • Spinal Canal / diagnostic imaging
  • Spinal Stenosis* / complications
  • Spinal Stenosis* / diagnostic imaging