Eukaryotic evolution: Spatial proteomics sheds light on mitochondrial reduction

Michelle M Leger; Courtney Stairs

doi:10.1016/j.cub.2022.10.039

Eukaryotic evolution: Spatial proteomics sheds light on mitochondrial reduction

Curr Biol. 2022 Dec 5;32(23):R1308-R1311. doi: 10.1016/j.cub.2022.10.039.

Authors

Michelle M Leger¹, Courtney Stairs²

Affiliations

¹ Institute of Evolutionary Biology (CSIC-Universitat Pompeu Fabra), Pg. Marítim de la Barceloneta 37-49, 08003 Barcelona, Spain. Electronic address: michelle.leger@ibe.upf-csic.es.
² Microbiology Research Group, Department of Biology, Lund University, Sölvegatan 35, 223 62 Lund, Sweden. Electronic address: courtney.stairs@biol.lu.se.

PMID: 36473440
DOI: 10.1016/j.cub.2022.10.039

Abstract

Multi-organelle spatial proteomics has revolutionized animal cell biology, but its use in protists has so far been limited. A new study delivers the first such proteome of a free-living protist, uncovering a previously overlooked function of highly reduced mitochondria.

Publication types

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MeSH terms

Eukaryota*
Proteomics*