Application of Radiomics in Predicting Treatment Response to Neoadjuvant Chemoradiotherapy in Locally Advanced Rectal Cancer: Strategies and Challenges

Rui Chen; Yan Fu; Xiaoping Yi; Qian Pei; Hongyan Zai; Bihong T Chen

doi:10.1155/2022/1590620

Application of Radiomics in Predicting Treatment Response to Neoadjuvant Chemoradiotherapy in Locally Advanced Rectal Cancer: Strategies and Challenges

J Oncol. 2022 Nov 26:2022:1590620. doi: 10.1155/2022/1590620. eCollection 2022.

Authors

Rui Chen¹, Yan Fu¹, Xiaoping Yi¹, Qian Pei¹, Hongyan Zai¹, Bihong T Chen²

Affiliations

¹ Department of Radiology, Xiangya Hospital, Central South University, Changsha 410008, Hunan, China.
² Department of Diagnostic Radiology, City of Hope National Medical Center, Duarte, CA, USA.

Abstract

Neoadjuvant chemoradiotherapy (nCRT) followed by total mesorectal excision is the standard treatment for locally advanced rectal cancer (LARC). A noninvasive preoperative prediction method should greatly assist in the evaluation of response to nCRT and for the development of a personalized strategy for patients with LARC. Assessment of nCRT relies on imaging and radiomics can extract valuable quantitative data from medical images. In this review, we examined the status of radiomic application for assessing response to nCRT in patients with LARC and indicated a potential direction for future research.

Publication types

Review