[Bacterial and fungal co-infection: an association of criminals to look for]

Rev Mal Respir. 2022 Dec;39(10):873-877. doi: 10.1016/j.rmr.2022.10.002. Epub 2022 Oct 28.
[Article in French]

Abstract

Introduction: Mucorales are fungi that cause opportunistic infections. Its incidence increases.

Case report: We report case of a 68-year-old woman with myelodysplastic syndrome responsible for prolonged neutropenia, hospitalized for pneumonia and sinusitis caused by Pseudomonas aeruginosa. But, despite antibiotic therapy, the patient's health deteriorated with discovery of systemic emboli on CT-scan and died. Sinus biopsies performed before her death diagnosed invasive fungal infection (Mucorales).

Conclusion: Mucorales co-infections are rare but have already been described. Any invasive fungal infection should be searched on the event of any clinical suspicion: ground (neutropenia), lack of response to well-conducted antibiotic therapy, rapidly unfavorable outcome. The presence of other microbiological documentation do not must stop the search of invasive fungal infection, because it could have short-term life-threatening impact.

Keywords: Infection fongique invasive; Invasive fungal infection; Pseudomonas aeruginosa.

Publication types

  • Case Reports
  • English Abstract

MeSH terms

  • Aged
  • Anti-Bacterial Agents / therapeutic use
  • Bacteria
  • Coinfection* / diagnosis
  • Criminals*
  • Female
  • Humans
  • Invasive Fungal Infections* / complications
  • Invasive Fungal Infections* / diagnosis
  • Mucormycosis* / complications
  • Mucormycosis* / diagnosis
  • Mycoses* / complications
  • Mycoses* / diagnosis
  • Mycoses* / drug therapy
  • Neutropenia*

Substances

  • Anti-Bacterial Agents