Bibliometric and Visualized Analysis of the Current Status on STING Signaling Pathway and Cancer

Zhongqi Lu; Qiang Fu; Jinyuan Sui; Ying Chang; Tiefeng Jin; Meihua Zhang

doi:10.1155/2022/5095176

Bibliometric and Visualized Analysis of the Current Status on STING Signaling Pathway and Cancer

J Oncol. 2022 Nov 23:2022:5095176. doi: 10.1155/2022/5095176. eCollection 2022.

Authors

Zhongqi Lu^{1

2}, Qiang Fu^{1

2}, Jinyuan Sui², Ying Chang^{1

2}, Tiefeng Jin², Meihua Zhang^{1

2

3}

Affiliations

¹ Department of Ultrasound Medicine, Affiliated Hospital of Yanbian University, Yanji 133000, Jilin, China.
² Tumor Research Center of Yanbian University, Yanji 133000, Jilin, China.
³ Health Examination Centre, Yanbian University Hospital, Yanji 133002, Jilin, China.

Abstract

Cancer, as the second leading cause of death worldwide, has become an ongoing public health challenge and its treatment has received much attention, with immunotherapy becoming a hot research topic in recent years. The interferon gene stimulating factor (STING)-mediated signaling pathway has a "double-edged sword" role in cancer, which plays different roles in different types and stages of tumors. In this paper, we discuss the current research status, cooperation, and hotspots of STING signaling pathway in cancer from 2008-2022 using CiteSpace software based on the literature of cancer and STING signaling pathway. In addition, we predicted future research trends in this field by analysis, and the results showed that the STING signaling pathway is rapidly increasing in cancer research, and its role in tumor microenvironment and immunotherapy has become a new hot spot in current research and will continue to receive high attention.