A Case of COVID-Associated Nephropathy (COVAN)

Taylor Craig; Moiz Ansari; Parker Foster; Yasir Abdelgadir; Amro Abdelghani; Pinky Jha

doi:10.7759/cureus.30872

A Case of COVID-Associated Nephropathy (COVAN)

Cureus. 2022 Oct 30;14(10):e30872. doi: 10.7759/cureus.30872. eCollection 2022 Oct.

Authors

Taylor Craig¹, Moiz Ansari², Parker Foster², Yasir Abdelgadir², Amro Abdelghani¹, Pinky Jha²

Affiliations

¹ Internal Medicine, Medical College of Wisconsin, Milwaukee, USA.
² Internal Medicine, Medical College of Wisconsin, Wauwatosa, USA.

Abstract

Collapsing glomerulopathy is a variant of focal segmental glomerulosclerosis (FSGS) causing rapid renal failure. There has been an emergence of these cases among African American patients with COVID-19, especially those with the apolipoprotein L1 (APOL1) allele. We present a case of an African American patient with COVID-19 who tested positive for the APOL1 allele in the setting of acute renal deterioration. This provides a partial explanation for the increased burden of kidney failure in this population. As cases of COVID-19 persist, COVID-associated nephropathy (COVAN) should be suspected in patients with acute kidney injury and treatment tailored accordingly.

Keywords: apolipoprotein l1; collapsing glomerulopathy; covan; covid; hiv associated nephropathy (hivan).

Publication types

Case Reports