Magnetically responsive chitosan-pectin films incorporating Fe3O4 nanoparticles with enhanced antimicrobial activity

Iratxe Zarandona; Daniela M Correia; Joana Moreira; Carlos M Costa; Senentxu Lanceros-Mendez; Pedro Guerrero; Koro de la Caba

doi:10.1016/j.ijbiomac.2022.11.286

Magnetically responsive chitosan-pectin films incorporating Fe₃O₄ nanoparticles with enhanced antimicrobial activity

Int J Biol Macromol. 2023 Feb 1:227:1070-1077. doi: 10.1016/j.ijbiomac.2022.11.286. Epub 2022 Dec 1.

Authors

Iratxe Zarandona¹, Daniela M Correia², Joana Moreira³, Carlos M Costa⁴, Senentxu Lanceros-Mendez⁵, Pedro Guerrero⁶, Koro de la Caba⁷

Affiliations

¹ BIOMAT Research Group, University of the Basque Country (UPV/EHU), Escuela de Ingeniería de Gipuzkoa, Plaza de Europa 1, 20018 Donostia-San Sebastián, Spain.
² Centre of Chemistry, University of Minho, 4710-053 Braga, Portugal.
³ Physics Centre of Minho and Porto Universities (CF-UM-UP), University of Minho, 4710-057 Braga, Portugal.
⁴ Physics Centre of Minho and Porto Universities (CF-UM-UP), University of Minho, 4710-057 Braga, Portugal; Institute of Science and Innovation for Bio-Sustainability (IB-S), University of Minho, 4710-053 Braga, Portugal; Laboratory of Physics for Materials and Emergent Technologies, LapMET, University of Minho, 4710-057 Braga, Portugal.
⁵ BCMaterials, Basque Center for Materials, Applications and Nanostructures, UPV/EHU Science Park, 48940 Leioa, Spain; Ikerbasque, Basque Foundation for Science, 48009 Bilbao, Spain. Electronic address: senentxu.lanceros@bcmaterials.net.
⁶ BIOMAT Research Group, University of the Basque Country (UPV/EHU), Escuela de Ingeniería de Gipuzkoa, Plaza de Europa 1, 20018 Donostia-San Sebastián, Spain; BCMaterials, Basque Center for Materials, Applications and Nanostructures, UPV/EHU Science Park, 48940 Leioa, Spain; Proteinmat materials SL, Avenida de Tolosa 72, 20018 Donostia-San Sebastián, Spain. Electronic address: pedromanuel.guerrero@ehu.es.
⁷ BIOMAT Research Group, University of the Basque Country (UPV/EHU), Escuela de Ingeniería de Gipuzkoa, Plaza de Europa 1, 20018 Donostia-San Sebastián, Spain; BCMaterials, Basque Center for Materials, Applications and Nanostructures, UPV/EHU Science Park, 48940 Leioa, Spain.

PMID: 36464184
DOI: 10.1016/j.ijbiomac.2022.11.286

Abstract

Chitosan-pectin films with iron oxide (Fe₃O₄) magnetic nanoparticles were prepared by solution casting in order to produce biopolymer based magnetically active materials. Infrared (FTIR) spectra indicated physical interactions between the matrix and nanoparticles, corroborated by differential scanning calorimetry (DSC) results. In addition, thermal characterization suggested that the interactions between chitosan, pectin and the nanoparticles resulted in a less compact structure, influencing the film mechanical properties. Regarding vibrating-sample magnetometry (VSM) and electrical analysis, chitosan-pectin films with Fe₃O₄ nanoparticles showed ferrimagnetic behavior, with an increase of the dielectric constant as the nanoparticle concentration increased. Furthermore, films displayed enhanced antimicrobial activity against Escherichia coli (Gram-negative) and Staphylococcus epidermidis (Gram-positive) bacteria. Therefore, chitosan-pectin films with Fe₃O₄ magnetic nanoparticles provide promising results for active and intelligent food packaging applications.

Keywords: Antimicrobial capacity; Chitosan-pectin films; Fe(3)O(4) nanoparticles; Magnetic properties.

MeSH terms

Anti-Bacterial Agents / chemistry
Anti-Bacterial Agents / pharmacology
Anti-Infective Agents* / chemistry
Anti-Infective Agents* / pharmacology
Chitosan* / chemistry
Chitosan* / pharmacology
Food Packaging / methods
Nanoparticles* / chemistry
Pectins / chemistry

Substances

Pectins
Chitosan
Anti-Infective Agents
Anti-Bacterial Agents