Characteristics Associated With Failure to Rescue After Open Abdominal Aortic Aneurysm Repair

J Surg Res. 2023 Mar:283:683-689. doi: 10.1016/j.jss.2022.11.018. Epub 2022 Nov 29.

Abstract

Introduction: Failure to Rescue (FTR), defined as mortality following a complication of care, is an important indicator of hospital care quality. Understanding risk factors associated with FTR in the elective Abdominal Aortic Aneurysm (AAA) population may help surgeons prevent operative mortality.

Methods: Elective open AAA repairs (2008-2018) were identified from Cerner's HealthFacts database using ICD-9 and ICD-10 diagnosis and procedure codes. Patient, hospital, and encounter characteristics were analyzed. Multivariate logistic regression models determined the relative contribution of patient and encounter characteristics leading to FTR.

Results: For 1761 patients who underwent open repair for nonruptured AAA, overall mortality was 6.1%. Of patients with one or more complications (40%), mortality was 9.6%, increasing to 21.5% for patients with ≥4 major complications. Complications of care most associated with death were myocardial infarction (MI), gastrointestinal (GI) bleeding, and pulmonary failure. After multivariable adjustment, FTR was associated with advanced age (odds ratio [OR] 1.19 for 5 y, 95% confidence interval [CI] 1.06-1.34); female sex (OR 1.74, 95% CI 1.12-2.70); congestive heart failure (OR 1.65, 95% CI 1.00-2.73); peptic ulcer disease (OR 3.99, 95% CI 1.18-13.5); diabetes (OR 4.90, 95% CI 1.90-12.6), and the number of complications of care.

Conclusions: Complications of care were common following open elective AAA repair. The complications with the highest mortality included MI, GI bleeding, and respiratory failure. FTR was associated with female sex, comorbidities, and increasing numbers of complications of care. Often, the lowest occurring complications had the highest FTR. Adopting gender-specific assessment tools, a protocol-driven approach for perioperative GI prophylaxis, and preoperative MI risk mitigation may lead to reduced FTR.

Keywords: Aortic abdominal aneurysm; Failure to rescue.

MeSH terms

  • Aortic Aneurysm, Abdominal* / surgery
  • Endovascular Procedures* / adverse effects
  • Female
  • Hospital Mortality
  • Humans
  • Myocardial Infarction* / etiology
  • Postoperative Complications / etiology
  • Retrospective Studies
  • Risk Factors
  • Treatment Outcome
  • Vascular Surgical Procedures / adverse effects