Wnt inhibitors reduce the unfolded protein response and enhance bortezomib-induced cell death in multiple myeloma

Blood Adv. 2023 Apr 11;7(7):1103-1107. doi: 10.1182/bloodadvances.2022008442.

Authors

Affiliations

¹ Center for Translational Immunology, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands.
² Department of Hematology, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands.
³ Oncode Institute, Utrecht, The Netherlands.
⁴ Department of Cell Biology, Center for Molecular Medicine, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands.

No abstract available

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Antineoplastic Agents* / pharmacology
Antineoplastic Agents* / therapeutic use
Bortezomib / pharmacology
Bortezomib / therapeutic use
Cell Death
Humans
Multiple Myeloma* / drug therapy
Multiple Myeloma* / metabolism
Unfolded Protein Response

Substances

Bortezomib
Antineoplastic Agents