Highly efficient and simultaneous magnetic solid phase extraction of heavy metal ions from water samples with l-Cysteine modified magnetic polyamidoamine dendrimers prior to high performance liquid chromatography

Abstract

Due to the strong metal-sulfur interaction between mercapto groups and metal ions, which can be used to functionalize polyamidoamine dendrimer decorated Fe₃O₄ nanoparticles for high enrichment of trace heavy metal ions from waters. Based on this concept, polyamidoamine dendrimer modified Fe₃O₄ nanomaterials were functionalized with l-Cysteine and a new magnetic solid phase extraction for rapid adsorption and separation of Hg²⁺, Pb²⁺, Co²⁺ and Cd²⁺ from waters was established. The factors affecting extraction efficiency have been optimized. Upon the optimal parameters, the established method provided good linear ranges of 0.1-200 μg L^-1 for Hg²⁺ and 0.05-200 μg L^-1 for Pb²⁺, Co²⁺ and Cd²⁺, and high sensitivity with limits of detection (LOD) of 0.018 μg L^-1, 0.014 μg L^-1, 0.013 μg L^-1 and 0.025 μg L^-1 for Cd²⁺, Pb²⁺, Co²⁺ and Hg²⁺, respectively. Real water samples were utilized to validate the proposed method, and achieved results revealed that the proposed method was sensitive, effective, stable and suitable for monitoring Pb²⁺, Cd²⁺, Co²⁺and Hg²⁺ in environmental waters. This work provided a novel strategy for the simultaneous analysis of target cations in waters, and a new direction for developing decoration method of nanomaterials according to specific purpose.

Keywords: Heavy metal ion; Magnetic polyamidoamine dendrimer; Magnetic solid phase extraction; l-cysteine.