From acute pulmonary embolism to post-pulmonary embolism sequelae

Vasa. 2023 Jan;52(1):29-37. doi: 10.1024/0301-1526/a001042. Epub 2022 Nov 29.

Abstract

Aim of this narrative review is to summarize the functional and hemodynamic implications of acute PE and PE sequelae, namely the post-PE syndrome. Briefly, we will first describe the epidemiology, diagnostic procedures, and therapeutic approaches of acute PE. Then, we will provide a definition of the post-PE syndrome and present the so far accumulated evidence regarding its epidemiology and the implications that arise for further diagnosis and treatment. Lastly, we will explore the most devastating long-term complication of PE, namely chronic thromboembolic pulmonary hypertension (CTEPH), and recent advances in its management.

Keywords: Pulmonary embolism; chronic thromboembolic pulmonary hypertension; echocardiography; post pulmonary embolism impairment; post pulmonary embolism syndrome.

Publication types

  • Review

MeSH terms

  • Acute Disease
  • Chronic Disease
  • Echocardiography / methods
  • Humans
  • Hypertension, Pulmonary* / diagnosis
  • Hypertension, Pulmonary* / epidemiology
  • Hypertension, Pulmonary* / etiology
  • Pulmonary Embolism* / diagnostic imaging
  • Pulmonary Embolism* / epidemiology
  • Risk Factors