Amoxicillin degradation ability of Bacillus cereus C1 isolated from catfish pond sludge in Vietnam

Heliyon. 2022 Nov 19;8(11):e11688. doi: 10.1016/j.heliyon.2022.e11688. eCollection 2022 Nov.

Abstract

The biological removal of antibiotic residue in the environment has earned great interest. This study presented the biodegradation of amoxicillin (AMX) using B. cereus C1 isolated from the catfish pond sludge in Vietnam. This AMX-degrading bacterial strain grew well in the range of temperatures between 25ΟC and 40ΟC under aerobic condition. In a culture medium containing nitrogen source of NH4Cl (1 g.L-1) alone, the bacterium showed a AMX degradation ability of 54%. The AMX degradation ability of this bacterial strain was the highest level of 94% in the culture medium with 1.5 g.L-1 of NH4Cl and 3 g.L-1 of glucose. B. cereus C1 exhibited a great antibiotic degradation capability on high AMX concentration of 250 μg.mL-1 of AMX with AMX removal efficiency of 84% in 16 h of cultivation.

Keywords: Amoxicillin degradation; Antibiotic resistance; Bacillus cereus.