Patient reported outcome measure domains and tools used among adolescents and young adults with cancer: A scoping review

Teyl Engstrom; Sarah Tanner; Wen Ray Lee; Cheryl Forbes; Rick Walker; Natalie Bradford; Jason D Pole

doi:10.1016/j.critrevonc.2022.103867

Patient reported outcome measure domains and tools used among adolescents and young adults with cancer: A scoping review

Crit Rev Oncol Hematol. 2023 Jan:181:103867. doi: 10.1016/j.critrevonc.2022.103867. Epub 2022 Nov 22.

Authors

Teyl Engstrom¹, Sarah Tanner¹, Wen Ray Lee¹, Cheryl Forbes¹, Rick Walker², Natalie Bradford³, Jason D Pole⁴

Affiliations

¹ Centre for Health Services Research, The University of Queensland, Herston, QLD, Australia.
² School of Medicine, The University of Queensland, Herston, QLD, Australia; Queensland Children's Hospital, Brisbane, QLD, Australia; Princess Alexandra Hospital, Brisbane, QLD, Australia.
³ Cancer and Palliative Care Outcomes Centre at Centre for Children's Health Research, Queensland University of Technology, Australia.
⁴ Centre for Health Services Research, The University of Queensland, Herston, QLD, Australia; The University of Toronto, Dalla Lana School of Public Health, Toronto, ON, Canada. Electronic address: j.pole@uq.edu.au.

PMID: 36427770
DOI: 10.1016/j.critrevonc.2022.103867

Abstract

Adolescent and young adult (AYA) cancer patients and survivors are growing and face with distinct issues from paediatric and older cancer survivors. Hence it is important the issues they encounter are measured using appropriate Patient Reported Outcome Measures (PROMs). We searched PubMed, EMBASE, CINAHL, and PsycINFO for articles including: (1) AYAs (ages 15-39), (2) Malignant neoplasms, and (3) PROMs. This resulted in 3566 unique articles, 523 were included for full text review, of which 175 were included. These studies included 203 distinct tools to measure PROMs across 31 domains. Physical function was most frequently measured domain, followed by social, emotional and mental health. The most commonly used tools were the EORTC QLQ-C30, HADS and SF-36. PROMs used in AYA cancer patients is a complex topic, this comprehensive review serves as a useful reference for researchers, clinicians and health services who want to better understand, and improve, outcomes among their patients.

Keywords: Adolescents and young adults; Cancer; Cancer survivors; Patient reported outcome measures; Patient reported outcomes.

Publication types

Review

MeSH terms

Adolescent
Adult
Cancer Survivors*
Child
Humans
Neoplasms* / epidemiology
Neoplasms* / psychology
Neoplasms* / therapy
Patient Reported Outcome Measures
Quality of Life / psychology
Survivors / psychology
Young Adult