Whole genome sequence data of Stenotrophomonas maltophilia SCAID WND1-2022 (370)

Ilya Korotetskiy; Ardak Jumagaziyeva; Bahkytzhan Kerimzhanova; Oleg Reva; Tatyana Kuznetsova; Sergey Shilov; Ludmila Ivanova; Natalya Zubenko; Raikhan Parenova; Zhanar Iskakbayeva; Bolatbek Baimakhanov; Aimana Bekmuhamedova

doi:10.1016/j.dib.2022.108694

Whole genome sequence data of Stenotrophomonas maltophilia SCAID WND1-2022 (370)

Data Brief. 2022 Oct 26:45:108694. doi: 10.1016/j.dib.2022.108694. eCollection 2022 Dec.

Affiliations

¹ JSC Scientific Center for Anti-Infectious Drugs, Almaty, Kazakhstan.
² Centre for Bioinformatics and Computational Biology, Department of Biochemistry, Genetics, and Microbiology, University of Pretoria, Pretoria, South Africa.
³ JSC National Research Center of Surgery named after Syzganov, Department of Vascular Surgery, Almaty, Kazakhstan.

Abstract

The whole genome sequence of a hospital infection agent, Stenotrophomonas maltophilia SCAID WND1-2022 (370), is reported. Raw PacBio generated reads and the genome sequence were deposited at NCBI under BioProject PRJNA754843. The genome comprises two replicons: 4,880,425 bp long chromosome comprising 4524 proteins and functional RNA coding genes and 38,606 bp long plasmid containing 40 CDS. Both replicons were methylated at third cytosine residues of ACCTC motifs. The taxonomic provenance of SCAID WND1-2022 (370) was determined by calculating sequence similarity to the reference genomes at NCBI that showed the highest 97.35% identity to S. maltophilia ISMMS4. Many antibiotic resistance and virulence genes were identified on the chromosome of S. maltophilia SCAID WND1-2022 (370), which include multiple efflux pumps, beta-lactamases, and genes involved in biofilm formation. The plasmid sequence was dissimilar to any known plasmid and seemingly was acquired from a distant microorganism. Plasmid-born genes possibly contributed to the virulence of the pathogens, but not to its drug resistance.

Keywords: Antimicrobial resistance; Hospital-associated pathogen; Methylation; Multidrug-resistant; Sequencing.