An extremely rare case of malignant jejunal mesenteric inflammatory myofibroblastic tumor in a 61-year-old male patient: A case report and literature review

Hamdi Al Shenawi; Salamah A Al-Shaibani; Suhair K Al Saad; Fedaa Al-Sindi; Khalid Al-Sindi; Noor Al Shenawi; Yahya Naguib; Rami Yaghan

doi:10.3389/fmed.2022.1042262

An extremely rare case of malignant jejunal mesenteric inflammatory myofibroblastic tumor in a 61-year-old male patient: A case report and literature review

Front Med (Lausanne). 2022 Nov 8:9:1042262. doi: 10.3389/fmed.2022.1042262. eCollection 2022.

Authors

Hamdi Al Shenawi¹, Salamah A Al-Shaibani², Suhair K Al Saad¹, Fedaa Al-Sindi³, Khalid Al-Sindi³, Noor Al Shenawi², Yahya Naguib^{4

5}, Rami Yaghan^{1

6}

Affiliations

¹ Department of Surgery, College of Medicine and Medical Sciences, Arabian Gulf University, Manama, Bahrain.
² College of Medicine and Medical Sciences, Arabian Gulf University, Manama, Bahrain.
³ Department of Pathology, King Hamad University Hospital, Busaiteen, Bahrain.
⁴ Department of Physiology, College of Medicine and Medical Sciences, Arabian Gulf University, Manama, Bahrain.
⁵ Department of Clinical Physiology, Faculty of Medicine, Menoufia University, Menoufia, Egypt.
⁶ Department of Surgery, Jordan University of Science and Technology, Irbid, Jordan.

Abstract

Introduction: A mesenteric inflammatory myofibroblastic tumor (IMT) is a rare solid tumor of intermediate malignant potential that affects children, adolescents, and young adults predominantly. IMT is mostly encountered in the lung. We report a case of malignant jejunal mesenteric IMT in a 61-year-old male patient who presented with vague abdominal pain and generalized weakness. CT scan revealed a mesenteric mass displacing the attached jejunum. Surgical resection was curative.

Discussion: An extensive literature review was performed to update and further analyze the already available data. A total of 35 cases with mesenteric IMT were reported previously. Only five cases of jejunal mesenteric IMT were reported. Mesenteric IMT demands vast effort to reveal the diagnosis due to its vagueness in the clinical presentation. Mesenteric IMT resembles each other in plenty of pathological and immunohistochemical characteristics.

Conclusion: To the best of our knowledge, this is the first case of malignant jejunal mesenteric IMT in the elderly. Surgical resection was curative.

Keywords: inflammatory; jejunum; mass; mesenchymal; mesentery; myofibroblastic; stromal; tumor.

Publication types

Case Reports