Use of Autologous Platelet Rich Plasma (A-PRP) for Postpartum Perineal Repair Failure: A Case Report

J Pers Med. 2022 Nov 17;12(11):1917. doi: 10.3390/jpm12111917.

Abstract

Perineal wound dehiscence is an uncommon but important postpartum complication. In many cases, it leads to extreme pain and urinary and defecation problems. For up to several weeks, it can interfere with the mother's daily activity, affecting psychosexual health and body image. The best way to manage perineal wound breakdown (resuturing vs. spontaneous closure) after childbirth remains controversial. A-PRP is the autologous human plasma containing an increased platelet concentration, rich in growth factors, and mediators with hemostatic, anti-inflammatory, and antimicrobial properties. It accelerates the natural healing process. Even though A-PRP is widely used in orthopedics and dermatology, its use in gynecological injuries is limited. We describe here a case of a woman with postpartum perineal dehiscence treated with A-PRP with positive outcomes.

Keywords: autologous platelet-rich plasma (A-PRP); episiotomy; perineal tear; postpartum complication; wound cicatrization; wound dehiscence.

Publication types

  • Case Reports

Grants and funding

This study was supported by a research fund from Regen Lab SA.