On Deterministic and Stochastic Multiple Pathogen Epidemic Models

Epidemiologia (Basel). 2021 Aug 12;2(3):325-337. doi: 10.3390/epidemiologia2030025.

Abstract

In this paper, we consider a stochastic epidemic model with two pathogens. In order to analyze the coexistence of two pathogens, we compute numerically the expectation time until extinction (the mean persistence time), which satisfies a stationary partial differential equation with degenerate variable coefficients, related to backward Kolmogorov equation. I use the finite element method in order to solve this equation, and we implement it in FreeFem++. The main conclusion of this paper is that the deterministic and stochastic epidemic models differ considerably in predicting coexistence of the two diseases and in the extinction outcome of one of them. Now, the main challenge would be to find an explanation for this result.

Keywords: epidemic models; finite element method; persistence time; stochastic differential equation.