Warthin tumor complicated with T-lymphoblastic lymphoma: a case report

Hua Xi Kou Qiang Yi Xue Za Zhi. 2022 Dec 1;40(6):727-730. doi: 10.7518/hxkq.2022.06.016.
[Article in English, Chinese]

Abstract

Warthin tumor is a benign salivary gland tumor comprising ductal epithelium and lymphoid stroma. To date, reports about the malignant transformations of intraepithelial and lymphoid components in Warthin tumor are extremely rare; lymphoid malignant transformation into B-cell lymphoma is particularly rare in combination with T-cell lymphoma. The case of Warthin tumor complicated with T-lymphoblastic lymphoma is reported to emphasize the importance of a careful light microscopic evaluation of lymphoid tissue in Warthin tumor for identifying occult lymphoma presence, reducing misdiagnosis and missed diagnosis, and determining a timely treatment.

Warthin瘤是一种良性唾液腺肿瘤,由导管上皮和淋巴样间质组成,迄今为止,有关Warthin瘤内淋巴成分恶变的报道罕见,且多恶变为B细胞淋巴瘤,合并T细胞淋巴瘤更尤为少见。本文报道1例Warthin瘤合并T淋巴母细胞淋巴瘤,旨在强调要对Warthin瘤内的淋巴组织进行仔细的光学显微镜评估,以识别隐匿性淋巴瘤的存在,减少误诊及漏诊并及时治疗。.

Keywords: T-lymphoblastic lymphoma; Warthin tumor; salivary gland.

Publication types

  • Case Reports

MeSH terms

  • Adenolymphoma* / complications
  • Adenolymphoma* / diagnosis
  • Adenolymphoma* / pathology
  • Epithelium / pathology
  • Humans
  • Parotid Neoplasms* / complications
  • Parotid Neoplasms* / diagnosis
  • Parotid Neoplasms* / pathology
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma* / complications
  • Salivary Gland Neoplasms*