In June 2019, comprehensive genomic profiling(CGP)tests was introduced to clinical practice under the national health insurance system in Japan. The Ministry of Health, Labour and Welfare(MHLW)established a network of designated hospitals for cancer genomic medicine(CGM)and the Center for Cancer Genomics and Advanced Therapeutics(C-CAT), the national datacenter for CGM. Clinical information as well as genomic data from the CGP tests are securely transferred to C- CAT. As of August 28th, 2022, a total of 39,431 data of clinical/genomic information are aggregated in C-CAT. The data are now open for sharing with not only the CGM hospitals but also other academic institutions and industries.