QUS characteristics in Normal Population: a Mini Review and our experience

Maryam Najafi; Minoo Najafi; Abbas Ali Keshtkar; Mojtaba Sedaghat; Ali Reza Khalilifard; Bagher Larijani; Zohreh Hamidi

doi:10.1007/s40200-022-01113-0

QUS characteristics in Normal Population: a Mini Review and our experience

J Diabetes Metab Disord. 2022 Sep 23;21(2):1635-1640. doi: 10.1007/s40200-022-01113-0. eCollection 2022 Dec.

Authors

Maryam Najafi¹, Minoo Najafi¹, Abbas Ali Keshtkar², Mojtaba Sedaghat³, Ali Reza Khalilifard⁴, Bagher Larijani⁴, Zohreh Hamidi¹

Affiliations

¹ Endocrinology and Metabolism Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, Islamic Republic of Iran.
² Department of Health Sciences Education Development, School of Public Health, Tehran University of Medical Sciences, Tehran, Islamic Republic of Iran.
³ Department of Community Medicine, Faculty of Medicine, Tehran University of Medical Sciences, Tehran, Islamic Republic of Iran.
⁴ Osteoporosis Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, Islamic Republic of Iran.

Abstract

Objectives: Quantitative ultrasound (QUS) is a bone densitometry method that is less expensive and more portable than DXA. It is also noninvasive. QUS parameters include speed of sound (SOS), broad band ultrasound attenuation (BUA), and stiffness index (SI). This study defined normal values of QUS parameters in Iranian men and women.

Methods: QUS of heels measured in 258 Iranian men and women, aged 20-76 y/o. They were participants of Iranian Multicenter Osteoporosis study (IMOS), selected by randomized sampling. QUS device was an Achilles+ (GE-Lunar) device.

Results: Percentiles of SI (2.5%, 50%, and 97.5%) determined. We found a good agreement between the Iranian reference values and western reference (used by device) value in defining normal and osteoporotic people (κ = 0.875).

Conclusion: Results from this study suggest that QUS of the heel may be a good method for diagnosis of low bone mass in different regions.

Keywords: Heel; Iran; Normal range; QUS.

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